Red Light Enhances Flavonoid and Phenolic Production in Cichorium spp. Callus Culture for Anti-Candida Properties

The pharmaceutical industry is increasingly focused on developing high-quality, safe, and effective medications, with a notable shift towards herbal medicines, which could constitute 60% of treatments in the next 15-20 years according to WHO projections. This trend is particularly relevant due to the rise of drug-resistant Candida species, including Candida albicans, which pose significant health risks, especially to immunocompromised patients. Exploring plant extracts as alternatives has gained momentum, utilizing their diverse bioactive compounds that demonstrate antimicrobial effects, including against Candida infections. Recent research highlights chicory as a promising source of anti-Candida agents, particularly through innovations in biotechnological methods such as tissue culture and the application of LED light as an elicitor to enhance secondary metabolite production. This study aims to optimize the use of red and blue LED light in the elicitation of flavonoids and phenolic compounds in chicory callus cultures, potentially leading to enhanced natural antifungal products to combat Candida infections.

Red Light Enhances Flavonoid and Phenolic Production in Cichorium spp. Callus Culture for Anti-Candida Properties

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